Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
This compound is a synthetic small molecule belonging to the biphenyl and pyrimidinediamine chemical classes. It is an experimental dihydrofolate reductase (DHFR) inhibitor with potent activity in vitro. The compound has demonstrated nanomolar inhibitory activity against Candida albicans DHFR, suggesting potential as an antifungal agent or as a lead structure for further development of DHFR-targeted therapies. There are no approved indications or clinical use reported; it remains at the preclinical/experimental stage[2][9][3].
- Other names
- 5-[ (3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yne -1-y l ] -6-methylpyrimidine -2,4-diamine5-[ (3R)-3-[ 3-methoxy -5-(4-methylphenyl ) phenyl ] but -1-y n -1-y l ] -6-methylpyrimidine -2,4-diamine
02
Targets
DHFR (Dihydrofolate reductase)
Beyond the preview
Go deeper on 5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on 5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine.